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Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization
Polyketides are a class of natural products with diverse structures and biological activities. The structural variability of aromatic products of fungal nonreducing, multidomain iterative polyketide synthases (NR-PKS group of IPKSs) results from regiospecific cyclizations of reactive poly-β-keto int...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872118/ https://ncbi.nlm.nih.gov/pubmed/19847268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08475 |
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