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Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins
Chaperonins are allosteric double-ring ATPases that mediate cellular protein folding. ATP binding and hydrolysis control opening and closing of the central chaperonin chamber, which transiently provides a protected environment for protein folding. During evolution, two strategies to close the chaper...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3339572/ https://ncbi.nlm.nih.gov/pubmed/17460696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1236 |
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