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Targeting the IGF-1R signaling and mechanisms for epigenetic gene silencing in human multiple myeloma

Multiple myeloma (MM) is a B cell malignancy characterized by the expansion of clonal plasmablast/plasma cells within the bone-marrow. It is well established that the bone-marrow microenvironment has a pivotal role in providing critical cytokines and cell–cell interactions to support the growth and...

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Detalhes bibliográficos
Main Authors: Jernberg-Wiklund, Helena, Nilsson, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Informa Healthcare 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339548/
https://ncbi.nlm.nih.gov/pubmed/22348393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03009734.2012.659293
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