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Targeting EZH2 in Multiple Myeloma—Multifaceted Anti-Tumor Activity
The enhancer of zeste homolog 2 (EZH2) is the enzymatic subunit of the polycomb repressive complex 2 (PRC2) that exerts important functions during normal development as well as disease. PRC2 through EZH2 tri-methylates histone H3 lysine tail residue 27 (H3K27me3), a modification associated with repr...
Gorde:
| Argitaratua izan da: | Epigenomes |
|---|---|
| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6370027/ https://ncbi.nlm.nih.gov/pubmed/30761216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/epigenomes2030016 |
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