ProBDNF Collapses Neurite Outgrowth of Primary Neurons by Activating RhoA

BACKGROUND: Neurons extend their dendrites and axons to build functional neural circuits, which are regulated by both positive and negative signals during development. Brain-derived neurotrophic factor (BDNF) is a positive regulator for neurite outgrowth and neuronal survival but the functions of it...

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Bibliographic Details
Main Authors: Sun, Ying, Lim, Yoon, Li, Fang, Liu, Shen, Lu, Jian-Jun, Haberberger, Rainer, Zhong, Jin-Hua, Zhou, Xin-Fu
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338794/
https://ncbi.nlm.nih.gov/pubmed/22558255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035883
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