TDP-43 Identified from a Genome Wide RNAi Screen for SOD1 Regulators

Amyotrophic Lateral Sclerosis (ALS) is a late-onset, progressive neurodegenerative disease affecting motor neurons in the brain stem and spinal cord leading to loss of voluntary muscular function and ultimately, death due to respiratory failure. A subset of ALS cases are familial and associated with...

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Bibliographic Details
Main Authors: Somalinga, Balajee R., Day, Cameron E., Wei, Shuguang, Roth, Michael G., Thomas, Philip J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338536/
https://ncbi.nlm.nih.gov/pubmed/22563406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035818
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