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Cytotoxicity of Superoxide Dismutase 1 in Cultured Cells Is Linked to Zn(2+) Chelation

Neurodegeneration in protein-misfolding disease is generally assigned to toxic function of small, soluble protein aggregates. Largely, these assignments are based on observations of cultured neural cells where the suspect protein material is titrated directly into the growth medium. In the present s...

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Hlavní autoři: Johansson, Ann-Sofi, Vestling, Monika, Zetterström, Per, Lang, Lisa, Leinartaitė, Lina, Karlström, Mikael, Danielsson, Jens, Marklund, Stefan L., Oliveberg, Mikael
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338499/
https://ncbi.nlm.nih.gov/pubmed/22558346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036104
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