Cytotoxicity of Superoxide Dismutase 1 in Cultured Cells Is Linked to Zn(2+) Chelation

Neurodegeneration in protein-misfolding disease is generally assigned to toxic function of small, soluble protein aggregates. Largely, these assignments are based on observations of cultured neural cells where the suspect protein material is titrated directly into the growth medium. In the present s...

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Détails bibliographiques
Auteurs principaux: Johansson, Ann-Sofi, Vestling, Monika, Zetterström, Per, Lang, Lisa, Leinartaitė, Lina, Karlström, Mikael, Danielsson, Jens, Marklund, Stefan L., Oliveberg, Mikael
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338499/
https://ncbi.nlm.nih.gov/pubmed/22558346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036104
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