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Eukaryotic topoisomerase I-DNA interaction is stabilized by helix curvature.
The influence of DNA structure on topoisomerase I-DNA interaction has been investigated using a high affinity binding site and mutant derivatives thereof. Parallel determinations of complex formation and helix structure in the absence of superhelical stress suggest that the interaction is intensifie...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1991
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333848/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1851553/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.6.1235 |
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