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Eukaryotic topoisomerase I-DNA interaction is stabilized by helix curvature.

The influence of DNA structure on topoisomerase I-DNA interaction has been investigated using a high affinity binding site and mutant derivatives thereof. Parallel determinations of complex formation and helix structure in the absence of superhelical stress suggest that the interaction is intensifie...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphov: Krogh, S, Mortensen, U H, Westergaard, O, Bonven, B J
Materialtyp: Artigo
Språk:Inglês
Utgiven: Oxford University Press 1991
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333848/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1851553/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.6.1235
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