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Eukaryotic topoisomerase I-DNA interaction is stabilized by helix curvature.

The influence of DNA structure on topoisomerase I-DNA interaction has been investigated using a high affinity binding site and mutant derivatives thereof. Parallel determinations of complex formation and helix structure in the absence of superhelical stress suggest that the interaction is intensifie...

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Bibliografske podrobnosti
Main Authors: Krogh, S, Mortensen, U H, Westergaard, O, Bonven, B J
Format: Artigo
Jezik:Inglês
Izdano: 1991
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC333848/
https://ncbi.nlm.nih.gov/pubmed/1851553
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