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The C-terminal helical bundle of the tetrameric prokaryotic sodium channel accelerates the inactivation rate

Most tetrameric channels have cytosolic domains to regulate their functions, including channel inactivation. Here we show that the cytosolic C-terminal region of NavSulP, a prokaryotic voltage-gated sodium channel cloned from Sulfitobacter pontiacus, accelerates channel inactivation. The crystal str...

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Detaylı Bibliyografya
Asıl Yazarlar: Irie, Katsumasa, Shimomura, Takushi, Fujiyoshi, Yoshinori
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337986/
https://ncbi.nlm.nih.gov/pubmed/22531178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1797
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