Comparative Study of the Gating Motif and C-type Inactivation in Prokaryotic Voltage-gated Sodium Channels

Prokaryotic voltage-gated sodium channels (Na(V)s) are homotetramers and are thought to inactivate through a single mechanism, named C-type inactivation. Here we report the voltage dependence and inactivation rate of the NaChBac channel from Bacillus halodurans, the first identified prokaryotic Na(V...

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Bibliografiske detaljer
Main Authors: Irie, Katsumasa, Kitagawa, Kazuya, Nagura, Hitoshi, Imai, Tomoya, Shimomura, Takushi, Fujiyoshi, Yoshinori
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Membrane Transport, Structure, Function, and Biogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823509/
https://ncbi.nlm.nih.gov/pubmed/19959480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.057455
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