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Hydrazine-mediated cyclization of Ugi products to synthesize novel 3-hydroxypyrazoles
This report discloses a novel concise synthesis of a series of 3-hydroxypyrazoles 5 via a tandem Ugi/debenzylation /hydrazine-mediated cyclization sequence. Herein, n-butyl isocyanide 4b was utilized as an alternative to classical convertible isocyanides enabling high yielding hydrazine-mediated cyc...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337763/ https://ncbi.nlm.nih.gov/pubmed/22544981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2012.03.033 |
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