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Facile and rapid route for the synthesis of novel conformationally constrained norstatine analogs via PADAM-cyclization methodology
The following report describes novel methodology for the rapid synthesis of unique conformationally constrained norstatine analogs of potential biological relevance. A PADAM (Passerini reaction – Amine Deprotection – Acyl Migration reaction) sequence is followed by a TFA-mediated microwave-assisted...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285404/ https://ncbi.nlm.nih.gov/pubmed/22368307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2011.12.073 |
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