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A unique role for ITK in survival of iNKT cells associated with the p53 dependent pathway in mice()

Invariant natural killer T (iNKT) cells play important roles in the immune response. ITK and TXK/RLK are Tec family kinases that are expressed in iNKT cells, with the expression level of ITK about 7-fold higher than that of TXK. Itk(−/−) mice have reduced iNKT cell frequency and numbers, with defect...

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Autori principali: Qi, Qian, Huang, Weishan, Bai, Yuting, Balmus, Gabriel, Weiss, Robert S., August, Avery
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337705/
https://ncbi.nlm.nih.gov/pubmed/22403441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102475
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