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A unique role for ITK in survival of iNKT cells associated with the p53 dependent pathway in mice()
Invariant natural killer T (iNKT) cells play important roles in the immune response. ITK and TXK/RLK are Tec family kinases that are expressed in iNKT cells, with the expression level of ITK about 7-fold higher than that of TXK. Itk(−/−) mice have reduced iNKT cell frequency and numbers, with defect...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337705/ https://ncbi.nlm.nih.gov/pubmed/22403441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102475 |
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