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Midostaurin does not prolong cardiac repolarization defined in a thorough electrocardiogram trial in healthy volunteers
PURPOSE: Midostaurin (PKC412) is a multitargeted tyrosine kinase inhibitor of FMS-like tyrosine kinase 3 receptor (FLT3), c-KIT, and other receptors. Midostaurin is active in patients with acute myeloid leukemia and systemic mastocytosis. Although no substantive risk for cardiac abnormalities has be...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer-Verlag
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337405/ https://ncbi.nlm.nih.gov/pubmed/22294470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-012-1825-y |
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