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Phase IB study of the FLT3 kinase inhibitor midostaurin with chemotherapy in younger newly diagnosed adult patients with acute myeloid leukemia

This phase 1b trial investigated several doses and schedules of midostaurin in combination with daunorubicin and cytarabine induction and high-dose cytarabine post-remission therapy in newly diagnosed patients with acute myeloid leukemia (AML). The discontinuation rate on the 50-mg twice-daily dose...

詳細記述

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書誌詳細
主要な著者: Stone, Richard M., Fischer, Thomas, Paquette, Ronald, Schiller, Gary, Schiffer, Charles A., Ehninger, Gerhard, Cortes, Jorge, Kantarjian, Hagop M., DeAngelo, Daniel J., Huntsman-Labed, Alice, Dutreix, Catherine, del Corral, Adam, Giles, Francis
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118284/
https://ncbi.nlm.nih.gov/pubmed/22627678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.115
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