Phase IB study of the FLT3 kinase inhibitor midostaurin with chemotherapy in younger newly diagnosed adult patients with acute myeloid leukemia

This phase 1b trial investigated several doses and schedules of midostaurin in combination with daunorubicin and cytarabine induction and high-dose cytarabine post-remission therapy in newly diagnosed patients with acute myeloid leukemia (AML). The discontinuation rate on the 50-mg twice-daily dose...

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Detalhes bibliográficos
Main Authors: Stone, Richard M., Fischer, Thomas, Paquette, Ronald, Schiller, Gary, Schiffer, Charles A., Ehninger, Gerhard, Cortes, Jorge, Kantarjian, Hagop M., DeAngelo, Daniel J., Huntsman-Labed, Alice, Dutreix, Catherine, del Corral, Adam, Giles, Francis
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118284/
https://ncbi.nlm.nih.gov/pubmed/22627678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.115
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