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Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2

Proteins of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family are activated by various cellular stresses, including DNA damage, premature termination codon and nutritional status, and induce appropriate cellular responses. The importance of PIKK functions in the maintenance of g...

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Autors principals: Izumi, Natsuko, Yamashita, Akio, Ohno, Shigeo
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337166/
https://ncbi.nlm.nih.gov/pubmed/22540023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.18926
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