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Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2
Proteins of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family are activated by various cellular stresses, including DNA damage, premature termination codon and nutritional status, and induce appropriate cellular responses. The importance of PIKK functions in the maintenance of g...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337166/ https://ncbi.nlm.nih.gov/pubmed/22540023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.18926 |
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