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Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2

Proteins of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family are activated by various cellular stresses, including DNA damage, premature termination codon and nutritional status, and induce appropriate cellular responses. The importance of PIKK functions in the maintenance of g...

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Библиографические подробности
Главные авторы: Izumi, Natsuko, Yamashita, Akio, Ohno, Shigeo
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337166/
https://ncbi.nlm.nih.gov/pubmed/22540023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.18926
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