Efficient SIVcpz replication in human lymphoid tissue requires viral matrix protein adaptation

SIVs infecting wild-living apes in west central Africa have crossed the species barrier to humans on at least four different occasions, one of which spawned the AIDS pandemic. Although the chimpanzee precursor of pandemic HIV-1 strains must have been able to infect humans, the capacity of SIVcpz str...

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Detalhes bibliográficos
Main Authors: Bibollet-Ruche, Frederic, Heigele, Anke, Keele, Brandon F., Easlick, Juliet L., Decker, Julie M., Takehisa, Jun, Learn, Gerald, Sharp, Paul M., Hahn, Beatrice H., Kirchhoff, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336991/
https://ncbi.nlm.nih.gov/pubmed/22505456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61429
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