Efficient SIVcpz replication in human lymphoid tissue requires viral matrix protein adaptation

SIVs infecting wild-living apes in west central Africa have crossed the species barrier to humans on at least four different occasions, one of which spawned the AIDS pandemic. Although the chimpanzee precursor of pandemic HIV-1 strains must have been able to infect humans, the capacity of SIVcpz str...

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Bibliographic Details
Main Authors: Bibollet-Ruche, Frederic, Heigele, Anke, Keele, Brandon F., Easlick, Juliet L., Decker, Julie M., Takehisa, Jun, Learn, Gerald, Sharp, Paul M., Hahn, Beatrice H., Kirchhoff, Frank
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336991/
https://ncbi.nlm.nih.gov/pubmed/22505456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61429
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