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SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer

An association between lymph node metastasis and poor prognosis in breast cancer was observed decades ago. However, the mechanisms by which tumor cells infiltrate the lymphatic system are not completely understood. Recently, it has been proposed that the lymphatic system has an active role in metast...

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Main Authors: Wang, Chu-An, Jedlicka, Paul, Patrick, Aaron N., Micalizzi, Douglas S., Lemmer, Kimberly C., Deitsch, Erin, Casás-Selves, Matias, Harrell, J. Chuck, Ford, Heide L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336979/
https://ncbi.nlm.nih.gov/pubmed/22466647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59858
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