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Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice

Cancer development, progression, and metastasis are highly dependent on angiogenesis. The use of antiangiogenic drugs has been proposed as a novel strategy to interfere with tumor growth, but cancer cells respond by developing strategies to escape these treatments. In particular, animal models show...

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Detalhes bibliográficos
Main Authors: Maione, Federica, Capano, Stefania, Regano, Donatella, Zentilin, Lorena, Giacca, Mauro, Casanovas, Oriol, Bussolino, Federico, Serini, Guido, Giraudo, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336974/
https://ncbi.nlm.nih.gov/pubmed/22484816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58976
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