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Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice

Cancer development, progression, and metastasis are highly dependent on angiogenesis. The use of antiangiogenic drugs has been proposed as a novel strategy to interfere with tumor growth, but cancer cells respond by developing strategies to escape these treatments. In particular, animal models show...

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Bibliografiske detaljer
Main Authors: Maione, Federica, Capano, Stefania, Regano, Donatella, Zentilin, Lorena, Giacca, Mauro, Casanovas, Oriol, Bussolino, Federico, Serini, Guido, Giraudo, Enrico
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336974/
https://ncbi.nlm.nih.gov/pubmed/22484816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58976
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