Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis

Cooperativity between oncogenic mutations is recognized as a fundamental feature of malignant transformation, and it may be mediated by synergistic regulation of the expression of pro- and antitumorigenic target genes. However, the mechanisms by which oncogenes and tumor suppressors coregulate downs...

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Autori principali: Anderson, Philip D., McKissic, Sydika A., Logan, Monica, Roh, Meejeon, Franco, Omar E., Wang, Jie, Doubinskaia, Irina, van Meer, Riet, Hayward, Simon W., Eischen, Christine M., Eltoum, Isam-Eldin, Abdulkadir, Sarki A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336973/
https://ncbi.nlm.nih.gov/pubmed/22484818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58540
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