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Tumorigenic Polyploid Cells Contain Elevated ROS and are Selectively Targeted by Antioxidant Treatment
Polyploidy has been linked to tumorigenicity mainly due to the chromosomal aberrations. Elevated reactive oxygen species (ROS) generation, on the other hand, has also been associated with oncogenic transformation in most cancer cells. However, a possible link between ploidy and ROS is largely unexpl...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156849/ https://ncbi.nlm.nih.gov/pubmed/21503880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22793 |
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