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Tumorigenic Polyploid Cells Contain Elevated ROS and are Selectively Targeted by Antioxidant Treatment

Polyploidy has been linked to tumorigenicity mainly due to the chromosomal aberrations. Elevated reactive oxygen species (ROS) generation, on the other hand, has also been associated with oncogenic transformation in most cancer cells. However, a possible link between ploidy and ROS is largely unexpl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Roh, Meejeon, van der Meer, Riet, Abdulkadir, Sarki A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156849/
https://ncbi.nlm.nih.gov/pubmed/21503880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22793
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