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Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress

Autophagy regulates cell survival and cell death upon various cellular stresses, yet the molecular signaling events involved are not well defined. Here, we established the function of a proteolytic Cyclin E fragment (p18-CycE) in DNA damage-induced autophagy, apoptosis, and senescence. p18-CycE was...

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Detalhes bibliográficos
Main Authors: Singh, Kamini, Matsuyama, Shigemi, Drazba, Judith A, Almasan, Alexandru
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336077/
https://ncbi.nlm.nih.gov/pubmed/22240589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.8.2.18600
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