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Siglecs as sensors of self in innate and adaptive immune responses

Siglecs are expressed on most white blood cells of the immune system, and are known to modulate the activity of cell signaling receptors via regulatory motifs in their cytoplasmic domains. This immunoglobulin sub-family of co-receptors recognize sialic acid containing glycans as ligands, which are f...

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Autori principali: Paulson, James C., Macauley, Matthew S., Kawasaki, Norihito
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335958/
https://ncbi.nlm.nih.gov/pubmed/22288608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2011.06362.x
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