Caricamento...

Role for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts

TopBP1 is critical for both DNA replication and checkpoint regulation in vertebrate cells. In this study, we have identified Rif1 as a binding partner of TopBP1 in Xenopus egg extracts. In addition, Rif1 also interacts with both ATM and the Mre11-Rad50-Nbs1 (MRN) complex, which are key regulators of...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Kumar, Sanjay, Yoo, Hae Yong, Kumagai, Akiko, Shevchenko, Anna, Shevchenko, Andrej, Dunphy, William G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335920/
https://ncbi.nlm.nih.gov/pubmed/22391207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.6.19636
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !