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The Role of Dicentric Chromosome Formation and Secondary Centromere Deletion in the Evolution of Myeloid Malignancy

Dicentric chromosomes have been identified as instigators of the genome instability associated with cancer, but this instability is often resolved by one of a number of different secondary events. These include centromere inactivation, inversion, and intercentromeric deletion. Deletion or excision o...

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Detalles Bibliográficos
Main Authors: MacKinnon, Ruth N., Campbell, Lynda J.
Formato: Artigo
Idioma:Inglês
Publicado: SAGE-Hindawi Access to Research 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335544/
https://ncbi.nlm.nih.gov/pubmed/22567363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/643628
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