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Genome organization and the role of centromeres in evolution of the erythroleukaemia cell line HEL

Background and objectives: The human erythroleukaemia (HEL) cell line has a highly rearranged genome. We matched whole chromosome analysis with cytogenomic microarray data to build a detailed description of these rearrangements. Methodology: We used a combination of single nucleotide polymorphism ar...

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Bibliografiska uppgifter
Huvudupphovsmän: MacKinnon, Ruth N., Wall, Meaghan, Zordan, Adrian, Nutalapati, Srilakshmi, Mercer, Bruce, Peverall, Joanne, Campbell, Lynda J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868402/
https://ncbi.nlm.nih.gov/pubmed/24481202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emph/eot020
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