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The Role of Dicentric Chromosome Formation and Secondary Centromere Deletion in the Evolution of Myeloid Malignancy

Dicentric chromosomes have been identified as instigators of the genome instability associated with cancer, but this instability is often resolved by one of a number of different secondary events. These include centromere inactivation, inversion, and intercentromeric deletion. Deletion or excision o...

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Bibliografische gegevens
Hoofdauteurs: MacKinnon, Ruth N., Campbell, Lynda J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE-Hindawi Access to Research 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335544/
https://ncbi.nlm.nih.gov/pubmed/22567363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/643628
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