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The Role of Dicentric Chromosome Formation and Secondary Centromere Deletion in the Evolution of Myeloid Malignancy

Dicentric chromosomes have been identified as instigators of the genome instability associated with cancer, but this instability is often resolved by one of a number of different secondary events. These include centromere inactivation, inversion, and intercentromeric deletion. Deletion or excision o...

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Bibliografiske detaljer
Main Authors: MacKinnon, Ruth N., Campbell, Lynda J.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE-Hindawi Access to Research 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335544/
https://ncbi.nlm.nih.gov/pubmed/22567363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/643628
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