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The Role of Dicentric Chromosome Formation and Secondary Centromere Deletion in the Evolution of Myeloid Malignancy

Dicentric chromosomes have been identified as instigators of the genome instability associated with cancer, but this instability is often resolved by one of a number of different secondary events. These include centromere inactivation, inversion, and intercentromeric deletion. Deletion or excision o...

詳細記述

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書誌詳細
主要な著者: MacKinnon, Ruth N., Campbell, Lynda J.
フォーマット: Artigo
言語:Inglês
出版事項: SAGE-Hindawi Access to Research 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335544/
https://ncbi.nlm.nih.gov/pubmed/22567363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/643628
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