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The Role of Dicentric Chromosome Formation and Secondary Centromere Deletion in the Evolution of Myeloid Malignancy

Dicentric chromosomes have been identified as instigators of the genome instability associated with cancer, but this instability is often resolved by one of a number of different secondary events. These include centromere inactivation, inversion, and intercentromeric deletion. Deletion or excision o...

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Detalhes bibliográficos
Main Authors: MacKinnon, Ruth N., Campbell, Lynda J.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335544/
https://ncbi.nlm.nih.gov/pubmed/22567363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/643628
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