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DNA methylation as a regulatory mechanism in rat gamma-crystallin gene expression.
We have investigated the methylation state of the rat gamma-crystallin genes in DNA from lens cells at different developmental stages as well as from kidney and heart cells. A clear correlation between the extent of demethylation of the promoter and 5' gene regions and the expression of these g...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1991
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC333536/ https://ncbi.nlm.nih.gov/pubmed/2011513 |
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