DNA methylation as a regulatory mechanism in rat gamma-crystallin gene expression.
We have investigated the methylation state of the rat gamma-crystallin genes in DNA from lens cells at different developmental stages as well as from kidney and heart cells. A clear correlation between the extent of demethylation of the promoter and 5' gene regions and the expression of these genes...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1991
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2011513/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.1.77 |
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