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DNA methylation as a regulatory mechanism in rat gamma-crystallin gene expression.

We have investigated the methylation state of the rat gamma-crystallin genes in DNA from lens cells at different developmental stages as well as from kidney and heart cells. A clear correlation between the extent of demethylation of the promoter and 5' gene regions and the expression of these g...

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Bibliografske podrobnosti
Main Authors: Peek, R, Niessen, R W, Schoenmakers, J G, Lubsen, N H
Format: Artigo
Jezik:Inglês
Izdano: 1991
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC333536/
https://ncbi.nlm.nih.gov/pubmed/2011513
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