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DNA methylation as a regulatory mechanism in rat gamma-crystallin gene expression.

We have investigated the methylation state of the rat gamma-crystallin genes in DNA from lens cells at different developmental stages as well as from kidney and heart cells. A clear correlation between the extent of demethylation of the promoter and 5' gene regions and the expression of these g...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Peek, R, Niessen, R W, Schoenmakers, J G, Lubsen, N H
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 1991
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333536/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2011513/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.1.77
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