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NMR Detection of Structures in the HIV-1 5´-Leader RNA that Regulate Genome Packaging
The 5´-leader of the HIV-1 genome regulates multiple functions during viral replication by mechanisms that have yet to be established. We developed an NMR approach that enabled direct detection of structural elements within the intact leader (712 nucleotide dimer) that are critical for genome packag...
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| Autores principales: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3335204/ https://ncbi.nlm.nih.gov/pubmed/21998393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1210460 |
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