Loading...

NMR Detection of Structures in the HIV-1 5´-Leader RNA that Regulate Genome Packaging

The 5´-leader of the HIV-1 genome regulates multiple functions during viral replication by mechanisms that have yet to be established. We developed an NMR approach that enabled direct detection of structural elements within the intact leader (712 nucleotide dimer) that are critical for genome packag...

Full description

Saved in:
Bibliographic Details
Main Authors: Lu, Kun, Heng, Xiao, Garyu, Lianko, Monti, Sarah, Garcia, Eric L., Kharytonchyk, Siarhei, Dorjsuren, Bilguujin, Kulandaivel, Gowry, Jones, Simonne, Hiremath, Atheeth, Divakaruni, Sai Sachin, LaCotti, Courtney, Barton, Shawn, Tummillo, Daniel, Hosic, Azra, Edme, Kedy, Albrecht, Sara, Telesnitsky, Alice, Summers, Michael F.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335204/
https://ncbi.nlm.nih.gov/pubmed/21998393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1210460
Tags: Add Tag
No Tags, Be the first to tag this record!