Structure of the HIV-1 RNA Packaging Signal

The 5′-leader of the HIV-1 genome contains conserved elements that direct selective packaging of the unspliced, dimeric viral RNA into assembling particles. Using a (2)H-edited NMR approach, we determined the structure of a 155-nucleotide region of the leader that is independently capable of directi...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Keane, Sarah C., Heng, Xiao, Lu, Kun, Kharytonchyk, Siarhei, Ramakrishnan, Venkateswaran, Carter, Gregory, Barton, Shawn, Hosic, Azra, Florwick, Alyssa, Santos, Justin, Bolden, Nicholas C., McCowin, Sayo, Case, David A., Johnson, Bruce, Salemi, Marco, Telesnitsky, Alice, Summers, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492308/
https://ncbi.nlm.nih.gov/pubmed/25999508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa9266
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