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Tau Phosphorylation and μ-Calpain Activation Mediate the Dexamethasone-Induced Inhibition on the Insulin-Stimulated Akt Phosphorylation

Evidence has suggested that insulin resistance (IR) or high levels of glucocorticoids (GCs) may be linked with the pathogenesis and/or progression of Alzheimer's disease (AD). Although studies have shown that a high level of GCs results in IR, little is known about the molecular details that li...

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Autors principals: Liu, Yudong, Su, Ying, Sun, Shenggang, Wang, Tao, Qiao, Xian, Run, Xiaoqin, Liang, Zhihou
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335002/
https://ncbi.nlm.nih.gov/pubmed/22536436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035783
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