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Stress Granules contribute to α-globin homeostasis in differentiating erythroid cells
Hemoglobin is the major biosynthetic product of developing erythroid cells. Assembly of hemoglobin requires the balanced production of globin protein and the oxygen-carrying heme moiety. The heme-regulated inhibitor kinase (HRI) participates in this process by phosphorylating eIF2α and inhibiting th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3334423/ https://ncbi.nlm.nih.gov/pubmed/22452989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.03.070 |
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