Role of polynucleotide kinase/phosphatase in mitochondrial DNA repair

Mutations in mitochondrial DNA (mtDNA) are implicated in a broad range of human diseases and in aging. Compared to nuclear DNA, mtDNA is more highly exposed to oxidative damage due to its proximity to the respiratory chain and the lack of protection afforded by chromatin-associated proteins. While r...

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Detaylı Bibliyografya
Asıl Yazarlar: Tahbaz, Nasser, Subedi, Sudip, Weinfeld, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Genome Integrity, Repair and Replication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3333865/
https://ncbi.nlm.nih.gov/pubmed/22210862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1245
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