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Stimulation of human eosinophil and neutrophil polymorphonuclear leukocyte chemotaxis and random migration by 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid.

A human platelet lipoxygenase-generated product of arachidonic acid, identified by thin-layer chromatographic and mass spectrometric properties as 12-L-hydroxy-5,8,10,14-eicosatertraenoic acid (HETE), was selectively chemotactic in vitro for human polymorphonuclear leukocytes (PMN), as compared to m...

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Pubblicato in:J Clin Invest
Autori principali: Goetzl,, E J, Woods, J M, Gorman, R R
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1977
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/830662/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108617
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