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Arachidonate metabolism via lipoxygenase and 12L-hydroperoxy-5,8,10,14-icosatetraenoic acid peroxidase sensitive to anti-inflammatory drugs.

The enzymes of arachidonate metabolism via the lipoxygenase pathway in human platelet cytosol have been characterized and partially purified. The lipoxygenase activity has a pH optimum of 7.3 and reaches half-maximal activity at an arachidonate concentration of 80 microM. The oxidation of arachidona...

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Detalhes bibliográficos
Main Authors: Siegel, M I, McConnell, R T, Porter, N A, Cuatrecasas, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC348259/
https://ncbi.nlm.nih.gov/pubmed/6767237
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