Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis.

Lesional epidermis of psoriasis has a probable reduction in the cyclic AMP/cyclic GMP ratio. This altered ratio may in part be responsible for the characteristic glycogen storage, rapid cell proliferation, and reduced differentiation in lesional epidermis. The concentrations of prostaglandins E2 and...

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Main Authors: Hammarström, S, Hamberg, M, Samuelsson, B, Duell, E A, Stawiski, M, Voorhees, J J
格式: Artigo
語言:Inglês
出版: 1975
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC388890/
https://ncbi.nlm.nih.gov/pubmed/1061097
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