Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis.

Lesional epidermis of psoriasis has a probable reduction in the cyclic AMP/cyclic GMP ratio. This altered ratio may in part be responsible for the characteristic glycogen storage, rapid cell proliferation, and reduced differentiation in lesional epidermis. The concentrations of prostaglandins E2 and...

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Detalhes bibliográficos
Main Authors: Hammarström, S, Hamberg, M, Samuelsson, B, Duell, E A, Stawiski, M, Voorhees, J J
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC388890/
https://ncbi.nlm.nih.gov/pubmed/1061097
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