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Introduction of a Disulfide Bond Leads to Stabilization and Crystallization of a Ricin Immunogen()
RTA1-33/44-198 is a catalytically inactive, single-domain derivative of the ricin toxin A-chain (RTA) engineered to serve as a stable protein scaffold for presentation of native immunogenic epitopes (Olson, et al., Protein Eng Des Sel 2004 17:391-7). To improve the stability and solubility of RTA1-3...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3332088/ https://ncbi.nlm.nih.gov/pubmed/21387408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22933 |
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