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TGF-β converts apoptotic stimuli into the signal for Th9 differentiation
Naturally arising CD4(+)CD25(+)FoxP3(+) regulatory T cells (nTregs) play an essential role in maintenance of immune homeostasis and peripheral tolerance. Previously, we reported that conventional CD4(+) and CD8(+) T cells undergo p53-induced CD28-dependent apoptosis (PICA) when stimulated with a com...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3331903/ https://ncbi.nlm.nih.gov/pubmed/22461692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102698 |
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