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TGF-β converts apoptotic stimuli into the signal for Th9 differentiation

Naturally arising CD4(+)CD25(+)FoxP3(+) regulatory T cells (nTregs) play an essential role in maintenance of immune homeostasis and peripheral tolerance. Previously, we reported that conventional CD4(+) and CD8(+) T cells undergo p53-induced CD28-dependent apoptosis (PICA) when stimulated with a com...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Takami, Mariko, Love, Robert B., Iwashima, Makio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331903/
https://ncbi.nlm.nih.gov/pubmed/22461692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102698
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