E3 Ligase Activity of XIAP RING Domain Is Required for XIAP-Mediated Cancer Cell Migration, but Not for Its RhoGDI Binding Activity

Although an increased expression level of XIAP is associated with cancer cell metastasis, the underlying molecular mechanisms remain largely unexplored. To verify the specific structural basis of XIAP for regulation of cancer cell migration, we introduced different XIAP domains into XIAP(−/−) HCT116...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Jinyi, Zhang, Dongyun, Luo, Wenjing, Yu, Jianxiu, Li, Jingxia, Yu, Yonghui, Zhang, Xinhai, Chen, Jingyuan, Wu, Xue-Ru, Huang, Chuanshu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330820/
https://ncbi.nlm.nih.gov/pubmed/22532870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035682
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